Name: Thallium Sulfate
CAS: 7446-18-6
EC Number: 231-201-3
Chemical Formular: Tl2SO4
Appearance: white prisms or dense white powder
Molecular Weight: 504.816 g/mol
Melting Point: 632 °C (1,170 °F; 905 K)
Boiling Point: n/a
Density: 6.77 g/cm3
Solubility in water: 4.87 g/100 mL (20 °C)
Exact Mass: 505.901 g/mol
Monoisotopic Mass: 505.901 g/mol
Topological Polar Surface Area: 88.6 A^2
Complexity: 62.2

Thallium Sulfate
99% Thallium Sulfate
99.9% Thallium Sulfate
99.99% Thallium Sulfate
99.999% Thallium Sulfate
Thallium Sulfate,customized specifications


According to the UN GHS revision 8

Version: 1.0

Creation Date: Oct 20, 2020

Revision Date: Oct 20, 2020

SECTION 1: Identification


GHS Product identifier

Product name

Thallium Sulfate


Other means of identification

Product number

Other names

thallium(1+) sulfate;CSF-Giftweizen;sulfuric acid dithallium(1+) salt


Recommended use of the chemical and restrictions on use

Identified uses

Industrial and scientific research uses.

Uses advised against

no data available


Supplier’s details


Elements China Limited


Building 2, No.5555, Shenzhuan Hwy, Shanghai , China



1.5Emergency phone number

Emergency phone number


Service hours

Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

SECTION 2: Hazard identification


Classification of the substance or mixture

Acute toxicity – Category 2, Oral

Skin irritation, Category 2

Specific target organ toxicity – repeated exposure, Category 1

Hazardous to the aquatic environment, long-term (Chronic) – Category Chronic 2


GHS label elements, including precautionary statements


Signal word


Hazard statement(s)

H300 Fatal if swallowed

H315 Causes skin irritation

H372 Causes damage to organs through prolonged or repeated exposure

H411 Toxic to aquatic life with long lasting effects

Precautionary statement(s)

P264 Wash … thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.


P301+P316 IF SWALLOWED: Get emergency medical help immediately.

P321 Specific treatment (see … on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/…

P332+P317 If skin irritation occurs: Get medical help.

P362+P364 Take off contaminated clothing and wash it before reuse.

P319 Get medical help if you feel unwell.

P391 Collect spillage.


P405 Store locked up.


P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.


Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients



Chemical nameCommon names and synonymsCAS numberEC number
Thallium SulfateDithallium sulphate7446-18-6231-201-3

SECTION 4: First-aid measures


Description of necessary first-aid measures

If inhaled

Refer for medical attention.

Following skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth. Give one or two glasses of water to drink. Refer immediately for medical attention.


Most important symptoms/effects, acute and delayed

Rated as extremely toxic. The probable oral lethal dose in humans is 5 to 50 mg/kg, or between 7 drops and 1 teaspoon for a 150-pound person. The mean lethal dose in an adult is probably about 1 gm of thallium sulfate. Chronic exposure causes hair loss starting 10 days after exposure and complete baldness in about a month. (EPA, 1998)


Indication of immediate medical attention and special treatment needed, if necessary

Absorption, Distribution and Excretion

Gave intravenous thallium sulfate to a small group of rats & simulated thallium kinetics on the basis of a three-compartment model. … concluded that a significant exchange of thallium occurred between the tissues & the intestinal contents … described as an entero-enteral cycle. … gave radioactive thallous nitrate & thallous sulfate orally to 1 pt with metastatic osteogenic sarcoma & found rate of excretion in urine to be 3.2% per day of amount remaining in body. thallium excretion in both urine & feces may persist for many weeks in spite of low plasma levels in poisoned patients.

SECTION 5: Fire-fighting measures


Suitable extinguishing media

Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty. Use water in flooding quantities as fog. Use “alcohol” foam, dry chemical or carbon dioxide. Wear positive pressure self-contained breathing apparatus when fighting fires involving this material.


Specific hazards arising from the chemical

When heated to decomposition, it emits very toxic fumes of thallium and sulfur oxide. (EPA, 1998)


Special protective actions for fire-fighters

In case of fire in the surroundings, use appropriate extinguishing media.

SECTION 6: Accidental release measures


Personal precautions, protective equipment and emergency procedures

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance and complete protective clothing. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.


Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance and complete protective clothing. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.


Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage


Precautions for safe handling

Handling in a well ventilated place.
Wear suitable protective clothing.
Avoid contact with skin and eyes.
Avoid formation of dust and aerosols.
Use non-sparking tools.
Prevent fire caused by electrostatic discharge steam.


Conditions for safe storage, including any incompatibilities

Provision to contain effluent from fire extinguishing. Store only in original container. Well closed. Separated from strong oxidants and food and feedstuffs. Store in an area without drain or sewer access.

SECTION 8: Exposure controls/personal protection


Control parameters

Occupational Exposure limit values

TLV: (inhalable fraction): 0.02 mg/m3, as TWA; (skin)

Biological limit values

no data available


Appropriate engineering controls

Ensure adequate ventilation.
Handle in accordance with good industrial hygiene and safety practice.
Set up emergency exits and the risk-elimination area.

8.3Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety goggles, face shield or eye protection in combination with breathing protection.

Skin protection

Protective gloves. Protective clothing.

Respiratory protection

Use closed system or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

Physical state

Thallium sulfate is an odorless white rhomboid prisms or a dense white powder. Density 6.77 g / cm3. Melting point 1170°F (632°C). Extremely toxic by ingestion. Very toxic by skin absorption and ingestion. A slow acting cumulative poison. Used as a rat poison, and an ant bait. Also used for analysis (testing for iodine in the presence of chlorine) and ozonometry. Not registered as a pesticide in the U.S.


White, rhomboid prisms



Melting point/freezing point


Boiling point or initial boiling point and boiling range

Decomposes (EPA, 1998)


Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Lower and upper explosion limit/flammability limit

no data available

Flash point

no data available

Auto-ignition temperature

no data available

Decomposition temperature

no data available


no data available

Kinematic viscosity

no data available


Solubility in 100 ml water at 0 deg C: 2.70 g, at 20 deg C: 4.87 g, at 100 deg C: 18.45 g

Partition coefficient n-octanol/water

no data available

Vapour pressure

Inappreciable (EPA, 1998)

Density and/or relative density

6.77g/mLat 25°C(lit.)

Relative vapour density

no data available

Particle characteristics

no data available

SECTION 10: Stability and reactivity



15 mg/cu m (as Tl). Thallium (soluble cmpds, as Tl)

Decomposes on heating. This produces toxic fumes including thallium and sulfur oxides. Reacts with strong oxidants.


Chemical stability

Very stable


Possibility of hazardous reactions

THALLIUM SULFATE has weak oxidizing and weak reducing powers. Redox reactions can however still occur.


Conditions to avoid

no data available


Incompatible materials

no data available


Hazardous decomposition products

no data available

SECTION 11: Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


no data available

Reproductive toxicity

no data available

STOT-single exposure

The substance is irritating to the eyes, skin and possibly the respiratory tract. The substance may cause effects on the gastrointestinal tract, central nervous system and peripheral nervous system. Exposure could cause hair loss. Ingestion of large amounts could cause effects on the cardiovascular system, kidneys and liver. Ingestion of large amounts could cause death. The effects may be delayed. Medical observation is indicated. See Notes.

STOT-repeated exposure

The substance may have effects on the nervous system. May cause hair loss.

Aspiration hazard

A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

SECTION 12: Ecological information



  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available


Persistence and degradability

no data available


Bioaccumulative potential

no data available


Mobility in soil

no data available


Other adverse effects

no data available

SECTION 13: Disposal considerations


Disposal methods


The material can be disposed of by removal to
a licensed chemical destruction plant or by controlled incineration
with flue gas scrubbing. Do not contaminate water, foodstuffs,
feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and
offered for recycling or reconditioning.
Alternatively, the packaging can be punctured to
make it unusable for other purposes and then be disposed of
in a sanitary landfill. Controlled incineration
with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information


UN Number

ADR/RID: UN1707 (For reference only, please check.)IMDG: UN1707 (For reference only, please check.)IATA: UN1707 (For reference only, please check.)


UN Proper Shipping Name

ADR/RID: THALLIUM COMPOUND, N.O.S. (For reference only, please check.)IMDG: THALLIUM COMPOUND, N.O.S. (For reference only, please check.)IATA: THALLIUM COMPOUND, N.O.S. (For reference only, please check.)


Transport hazard class(es)

ADR/RID: 6.1 (For reference only, please check.)IMDG: 6.1 (For reference only, please check.)IATA: 6.1 (For reference only, please check.)


Packing group, if applicable

ADR/RID: II (For reference only, please check.)IMDG: II (For reference only, please check.)IATA: II (For reference only, please check.)


Environmental hazards



Special precautions for user

no data available


Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information


Safety, health and environmental regulations specific for the product in question

Chemical nameCommon names and synonymsCAS numberEC number
Thallium SulfateDithallium sulphate7446-18-6231-201-3
European Inventory of Existing Commercial Chemical Substances (EINECS)Listed.
EC InventoryListed.
United States Toxic Substances Control Act (TSCA) InventoryListed.
China Catalog of Hazardous chemicals 2015Listed.
New Zealand Inventory of Chemicals (NZIoC)Listed.
Philippines Inventory of Chemicals and Chemical Substances
Vietnam National Chemical InventoryListed.
Chinese Chemical Inventory of Existing Chemical Substances (China
Korea Existing Chemicals List (KECL)Listed.

SECTION 16: Other information

Information on revision

Creation DateOct 20, 2020
Revision DateOct 20, 2020

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS – The International Chemical Safety Cards (ICSC), website:
  • HSDB – Hazardous Substances Data Bank, website:
  • IARC – International Agency for Research on Cancer, website:
  • eChemPortal – The Global Portal to Information on Chemical Substances by OECD, website:
  • CAMEO Chemicals, website:
  • ChemIDplus, website:
  • ERG – Emergency Response Guidebook by U.S. Department of Transportation, website:
  • Germany GESTIS-database on hazard substance, website:
  • ECHA – European Chemicals Agency, website:

Other Information

The symptoms of neurological disorders do not become manifest until after a few days.Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.See ICSCs 0077 and 1221.

Any questions regarding this SDS, Please send your inquiry to [email protected]

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information in this document is based on the present state of our
knowledge and is applicable to the product with regard to appropriate safety precautions. It does not
represent any guarantee of the properties of the product. We as supplier shall not be held liable for any
damage resulting from handling or from contact with the above product.

Chemical Formular:O4STl2
PubChem CID:24833
IUPAC Name:thallium(1+);sulfate
Canonical SMILES:[O-]S(=O)(=O)[O-].[Tl+].[Tl+]
Globally Harmonized System of Classification
Globally Harmonized System of Classification
Globally Harmonized System of Classification
GHS Hazard Statements:H300-H315-H372
Hazard Codes:T+, Xi, N
Risk Codes:R28-38-48/25-51/53
Precautionary Statement Codes:P260-P280g-P301+P310a-P321-P405-P501a
Flash Point:n/a

Thallium(I) sulfate
Dithallium(1+) sulfate
Sulfuric acid
dithallium (1+) salt
Thallous sulfate

ThalliumThallium is a chemical element with the symbol Tl and atomic number 81.
Thallium is a gray post-transition metal that is not found free in nature.
When isolated, thallium resembles tin, but discolors when exposed to air.
Chemists William Crookes and Claude-Auguste Lamy discovered thallium independently in 1861, in residues of sulfuric acid production.

OxygenOxygen is the chemical element with the symbol O and atomic number 8, meaning its nucleus has 8 protons.
Oxygen is a member of the chalcogen group on the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as well as with other compounds.
Dioxygen is used in cellular respiration and many major classes of organic molecules in living organisms contain oxygen, such as proteins, nucleic acids, carbohydrates, and fats, as do the major constituent inorganic compounds of animal shells, teeth, and bone.
Oxygen was isolated by Michael Sendivogius before 1604, but it is commonly believed that the element was discovered independently by Carl Wilhelm Scheele, in Uppsala, in 1773 or earlier, and Joseph Priestley in Wiltshire, in 1774.

SulfurSulfur (in non-scientific British use also sulphur) is a chemical element with the symbol S and atomic number 16.
It is abundant, multivalent, and nonmetallic. Under normal conditions, sulfur atoms form cyclic octatomic molecules with a chemical formula S8.
Elemental sulfur is a bright yellow, crystalline solid at room temperature.
Sulfur burns with a blue flame with formation of sulfur dioxide, which has a suffocating and irritating odor.
Sulfur is insoluble in water but soluble in carbon disulfide and, to a lesser extent, in other nonpolar organic solvents, such as benzene and toluene.

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